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Parkinson disease

In Parkinson disease, the exact cause and pathogenesis of the disease is still unknown. Degenerative lesions of the basal ganglia and loss of dopamine serves as a neurotransmitter have been observed.

Because the extrapyramidal system exerts an inhibitory effect on the autonomic nervous reflex that controls urination, any failure that causes neurogenic overactivity (hyperreflexia) in detrusor function, which is the most common urodynamic finding in disease. 

The distensibility is normal, the synergistic clamp remains smooth along with the bar even in slow relaxation. Urinary tract symptoms’ are irritating, obstructive or mixed.

Therapeutically in Parkinson’s disease, anticholinergics are administered or radical prostatectomy is performed if an urodynamic cystical obstacle is observed.